Document Type : Meta-Analyses

Authors

1 Department of sports Biomechanics, Faculty of Sport Science and Physical Education, Central Tehran Branch, Islamic Azad University, Tehran, Iran.

2 Department of Sport Biomechanics, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran.

3 Department of Ergonomics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

4 Department of sports Biomechanics, Faculty of Sport Science and Physical Education, Central Tehran Branch, Islamic azad University, Tehran, Iran

10.30476/jrsr.2024.103011.1493

Abstract

Background: Ensuring the safety and functional independence of older people is becoming increasingly important. Fall-prevention guidelines emphasize the use of highly challenging training modalities to reduce fall risk. Therefore, this systematic review and meta-analysis examined the effects of combined training (CT) on functionality, balance, and gait speed in older adults.
Methods: A systematic search was conducted in four electronic databases—PubMed, SCOPUS, Cochrane Central, and Web of Science—from inception to June 2, 2024. Standardized mean differences (SMDs), weighted mean differences (WMDs), and 95% confidence intervals (CIs) were calculated using fixed- or random-effects models, depending on heterogeneity.
Results: Twelve studies involving 570 participants met the inclusion criteria. Meta-analysis indicated that CT significantly improved functionality (SMD = 0.64; 95% CI: 0.34–0.93; p = 0.003), balance (SMD = 0.65; 95% CI: 0.39–0.90; p = 0.001), and gait speed (SMD = 1.18; 95% CI: 0.76–1.59; p = 0.001). Furthermore, CT was superior to traditional training (TT) in enhancing functionality (SMD = 0.50; 95% CI: 0.28–0.73; p = 0.001).
Conclusion: This meta-analysis demonstrates that combined training has a significant positive effect on functionality, balance, and gait speed in older adults. Compared with traditional training, CT yields greater improvements in functional performance. Therefore, CT is an effective and practical method for enhancing physical function and mobility in older people.

Highlights

Amirali Jafarnezhadgero

Keywords

  1. Rudnicka E, Napierała P, Podfigurna A, Męczekalski B, Smolarczyk R, Grymowicz M. The World Health Organization (WHO) approach to healthy ageing. Maturitas 2020;139:6-11.
  2. Gobbens RJ, Luijkx KG, Wijnen-Sponselee MT, Schols JM. Toward a conceptual definition of frail community dwelling older people. Nursing outlook 2010;58:76-86.
  3. Bauermeister S, Sutton G, Mon-Williams M, Wilkie R, Graveson J, Cracknell A, Wilkinson C, Holt R, Bunce D. Intraindividual variability and falls in older adults. Neuropsychology 2017;31:20.
  4. Pfortmueller C, Lindner G, Exadaktylos A. Reducing fall risk in the elderly: risk factors and fall prevention, a systematic review. Minerva Med 2014;105:275-81.
  5. Cuevas-Trisan R. Balance problems and fall risks in the elderly. Clinics in geriatric medicine 2019;35:173-83.
  6. Cuevas-Trisan R. Balance problems and fall risks in the elderly. Physical Medicine and Rehabilitation Clinics 2017;28:727-37.
  7. Oliveira MRd, Inokuti TT, Bispo NNdC, Oliveira DAdAP, Oliveira RFd, Silva Jr RAd. Elderly individuals with increased risk of falls show postural balance impairment. Fisioterapia em Movimento 2015;28:269-76.
  8. Thomas E, Battaglia G, Patti A, Brusa J, Leonardi V, Palma A, Bellafiore M. Physical activity programs for balance and fall prevention in elderly: A systematic review. Medicine 2019;98:e16218.
  9. Ronthal M. Gait disorders and falls in the elderly. Medical Clinics 2019;103:203-13.
  10. Jadczak AD, Makwana N, Luscombe-Marsh N, Visvanathan R, Schultz TJ. Effectiveness of exercise interventions on physical function in community-dwelling frail older people: an umbrella review of systematic reviews. JBI Evidence Synthesis 2018;16:752-75.
  11. Falck RS, Davis JC, Best JR, Crockett RA, Liu-Ambrose T. Impact of exercise training on physical and cognitive function among older adults: a systematic review and meta-analysis. Neurobiology of aging 2019;79:119-30.
  12. de Labra C, Guimaraes-Pinheiro C, Maseda A, Lorenzo T, Millán-Calenti JC. Effects of physical exercise interventions in frail older adults: a systematic review of randomized controlled trials. BMC geriatrics 2015;15:1-16.
  13. Grgic J, Schoenfeld BJ, Davies TB, Lazinica B, Krieger JW, Pedisic Z. Effect of resistance training frequency on gains in muscular strength: a systematic review and meta-analysis. Sports Medicine 2018;48:1207-20.
  14. Silva MR, Alberton CL, Portella EG, Nunes GN, Martin DG, Pinto SS. Water-based aerobic and combined training in elderly women: Effects on functional capacity and quality of life. Experimental gerontology 2018;106:54-60.
  15. [Hou L, Lei Y, Li X, Huo C, Jia X, Yang J, Xu R, Wang X-M. Effect of protein supplementation combined with resistance training on muscle mass, strength and function in the elderly: a systematic review and meta-analysis. The Journal of nutrition, health and aging 2019;23:451-8.
  16. Arienti C, Lazzarini SG, Pollock A, Negrini S. Rehabilitation interventions for improving balance following stroke: An overview of systematic reviews. PloS one 2019;14:e0219781.
  17. Lesinski M, Hortobágyi T, Muehlbauer T, Gollhofer A, Granacher U. Effects of balance training on balance performance in healthy older adults: a systematic review and meta-analysis. Sports medicine 2015;45:1721-38.
  18. Lopopolo RB, Greco M, Sullivan D, Craik RL, Mangione KK. Effect of therapeutic exercise on gait speed in community-dwelling elderly people: a meta-analysis. Physical therapy 2006;86:520-40.
  19. Van Abbema R, De Greef M, Crajé C, Krijnen W, Hobbelen H, Van Der Schans C. What type, or combination of exercise can improve preferred gait speed in older adults? A meta-analysis. BMC geriatrics 2015;15:1-16.
  20. Hortobágyi T, Lesinski M, Gäbler M, VanSwearingen JM, Malatesta D, Granacher U. Effects of three types of exercise interventions on healthy old adults’ gait speed: a systematic review and meta-analysis. Sports medicine 2015;45:1627-43.
  21. Lemos ECWM, Guadagnin EC, Mota CB. Influence of strength training and multicomponent training on the functionality of older adults: systematic review and meta-analysis. Revista Brasileira de Cineantropometria & Desempenho Humano 2020;22:e60707.
  22. Labata-Lezaun N, Gonzalez-Rueda V, Llurda-Almuzara L, Lopez-de-Celis C, Rodriguez-Sanz J, Bosch J, Vicente-Rodriguez G, Gorczakowska D, Araluze-Arizti P, Perez-Bellmunt A. Effectiveness of multicomponent training on physical performance in older adults: A systematic review and meta-analysis. Archives of gerontology and geriatrics 2023;104:104838.
  23. Weng W-H, Cheng Y-H, Yang T-H, Lee S-J, Yang Y-R, Wang R-Y. Effects of strength exercises combined with other training on physical performance in frail older adults: A systematic review and meta-analysis. Archives of gerontology and geriatrics 2022;102:104757.
  24. Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. bmj 2021;372.
  25. Landis JR, Koch GG. The measurement of observer agreement for categorical data. biometrics 1977:159-74.
  26. Albanese E, Bütikofer L, Armijo‐Olivo S, Ha C, Egger M. Construct validity of the Physiotherapy Evidence Database (PEDro) quality scale for randomized trials: Item response theory and factor analyses. Research Synthesis Methods 2020;11:227-36.
  27. Labanca L, Iovine R, Bragonzoni L, Barone G, Farella G, Benedetti MG. Instrumented platforms for balance and proprioceptive assessment in patients with total knee replacement: A systematic review and meta-analysis. Gait & Posture 2020.
  28. Montgomery PG, Pyne DB, Minahan CL. The physical and physiological demands of basketball training and competition. International journal of sports physiology and performance 2010;5:75-86.
  29. [Duval S, Tweedie R. Trim and fill: a simple funnel‐plot–based method of testing and adjusting for publication bias in meta‐analysis. Biometrics 2000;56:455-63.
  30. Abbasi A, Sadeghi H, Tabrizi HB, Bagheri K, Ghasemizad A, Asl A. Effect of whole body vibration, aquatic balance and combined training on neuromuscular performance, balance and walking ability in male elderly able-bodied individual. World Applied Sciences Journal 2011;15:84-91.
  31. Wang R-Y, Wang Y-L, Cheng F-Y, Chao Y-H, Chen C-L, Yang Y-R. Effects of combined exercise on gait variability in community-dwelling older adults. Age 2015;37:1-8.
  32. Holviala J, Kraemer W, Sillanpää E, Karppinen H, Avela J, Kauhanen A, Häkkinen A, Häkkinen K. Effects of strength, endurance and combined training on muscle strength, walking speed and dynamic balance in aging men. European journal of applied physiology 2012;112:1335-47.
  33. Islam MM, Nasu E, Rogers ME, Koizumi D, Rogers NL, Takeshima N. Effects of combined sensory and muscular training on balance in Japanese older adults. Preventive medicine 2004;39:1148-55.
  34. Fahlman M, Morgan A, McNevin N, Topp R, Boardley D. Combination training and resistance training as effective interventions to improve functioning in elders. Journal of Aging and Physical Activity 2007;15:195-205.
  35. Zouita S, Zouhal H, Ferchichi H, Paillard T, Dziri C, Hackney AC, Laher I, Granacher U, Ben Moussa Zouita A. Effects of combined balance and strength training on measures of balance and muscle strength in older women with a history of falls. Frontiers in physiology 2020;11:619016.
  36. Barzegari M, Shojaedin SS, Bayat Tork M. The effect of 8-week strength training, balance training and combined training on the dynamic and static balance of the elderly inactive men. Physical Treatments-Specific Physical Therapy Journal 2019;9:15-22.
  37. Mosayebi Samani K, Davari F, Faramarzi M. The effects of combined aerobic and balance training on balance in elderly women. Iranian Journal of Ageing 2015;10:26-35.
  38. Park H, Kim KJ, Komatsu T, Park SK, Mutoh Y. Effect of combined exercise training on bone, body balance, and gait ability: a randomized controlled study in community-dwelling elderly women. Journal of bone and mineral metabolism 2008;26:254-9.
  39. Im JY, Bang HS, Seo DY. The effects of 12 weeks of a combined exercise program on physical function and hormonal status in elderly Korean women. International journal of environmental research and public health 2019;16:4196.
  40. Ghaderian M, Ghasemi GA, Lenjannejadian S, Sadeghi Demneh E. The Effect of Combined Training on Older Men’s Walking and Turning Kinetics. Physical & Occupational Therapy In Geriatrics 2023;41:362-82.
  41. Larsson L, Degens H, Li M, Salviati L, Lee YI, Thompson W, Kirkland JL, Sandri M. Sarcopenia: aging-related loss of muscle mass and function. Physiological reviews 2019;99:427-511.
  42. Shephard R. Physical activity and aging. Taylor & Francis; 2024.
  43. Distefano G, Goodpaster BH. Effects of exercise and aging on skeletal muscle. Cold Spring Harbor perspectives in medicine 2018;8:a029785.
  44. Ciprandi D, Bertozzi F, Zago M, Sforza C, Galvani C. Associations between objectively measured physical activity levels and physical fitness and health-related quality of life in elderly women. Sport Sciences for Health 2018;14:183-91.
  45. Tittle CR. Control balance: Toward a general theory of deviance. Routledge; 2018.
  46. Ivanenko Y, Gurfinkel VS. Human postural control. Frontiers in neuroscience 2018;12:301583.
  47. Low DC, Walsh GS, Arkesteijn M. Effectiveness of exercise interventions to improve postural control in older adults: a systematic review and meta-analyses of centre of pressure measurements. Sports medicine 2017;47:101-12.
  48. Lopez P, Pinto RS, Radaelli R, Rech A, Grazioli R, Izquierdo M, Cadore EL. Benefits of resistance training in physically frail elderly: a systematic review. Aging clinical and experimental research 2018;30:889-99.
  49. Fragala MS, Cadore EL, Dorgo S, Izquierdo M, Kraemer WJ, Peterson MD, Ryan ED. Resistance training for older adults: position statement from the national strength and conditioning association. The Journal of Strength & Conditioning Research 2019;33.
  50. Sherrington C, Michaleff ZA, Fairhall N, Paul SS, Tiedemann A, Whitney J, Cumming RG, Herbert RD, Close JC, Lord SR. Exercise to prevent falls in older adults: an updated systematic review and meta-analysis. British journal of sports medicine 2017;51:1750-8.
  51. Tricco AC, Thomas SM, Veroniki AA, Hamid JS, Cogo E, Strifler L, Khan PA, Robson R, Sibley KM, MacDonald H. Comparisons of interventions for preventing falls in older adults: a systematic review and meta-analysis. Jama 2017;318:1687-99.
  52. Lusardi MM, Fritz S, Middleton A, Allison L, Wingood M, Phillips E, Criss M, Verma S, Osborne J, Chui KK. Determining risk of falls in community dwelling older adults: a systematic review and meta-analysis using posttest probability. Journal of geriatric physical therapy 2017;40:1-36.
  53. Yang N-P, Hsu N-W, Lin C-H, Chen H-C, Tsao H-M, Lo S-S, Chou P. Relationship between muscle strength and fall episodes among the elderly: the Yilan study, Taiwan. BMC geriatrics 2018;18:1-7.
  54. Martínez-Velilla N, Casas-Herrero A, Zambom-Ferraresi F, de Asteasu MLS, Lucia A, Galbete A, García-Baztán A, Alonso-Renedo J, González-Glaría B, Gonzalo-Lázaro M. Effect of exercise intervention on functional decline in very elderly patients during acute hospitalization: a randomized clinical trial. JAMA internal medicine 2019;179:28-36.
  55. Pahlevanian AA, Najarian R, Adabi S, Mirshoja MS. The prevalence of fall and related factors in Iranian elderly: a systematic review. Archives of Rehabilitation 2020;21:286-303.
  56. Ming Y, Zecevic AA, Hunter SW, Miao W, Tirona RG. Medication review in preventing older adults’ fall-related injury: a systematic review & meta-analysis. Canadian geriatrics journal 2021;24:237.
  57. Dautzenberg L, Beglinger S, Tsokani S, Zevgiti S, Raijmann RC, Rodondi N, Scholten RJ, Rutjes AW, Di Nisio M, Emmelot‐Vonk M. Interventions for preventing falls and fall‐related fractures in community‐dwelling older adults: a systematic review and network meta‐analysis. Journal of the American Geriatrics Society 2021;69:2973-84.